Uncategorized A new mechanism for future anti-cancer drugs?

A new mechanism for future anti-cancer drugs?

A research team at the Medical University of South Carolina (MUSC) has discovered a new mechanism for a class of anti-cancer drugs known as E1 inhibitors. Their findings, published in Nature Communications on December 4, 2018, reveal a novel binding site that will promote drug design of more efficient E1 inhibitors. The team was led …

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Uncategorized Self-control strategies involves  more than willpower 

Self-control strategies involves  more than willpower 

“Temptations are arguably more readily available, more creatively engineered, and cheaper than any time in history,” Duckworth says. “Junk food gets tastier and cheaper every year. And then there’s video games, social media, the list goes on. In parallel, there are public policy issues such as obesity, educational underachievement, and undersaving that result, in part, …

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Uncategorized Physiological age and mortality

Physiological age and mortality

It’s often said: It’s not how old you are, it’s how old you feel. New research shows that physiological age is a better predictor of survival than chronological age. The study is published today in the European Journal of Preventive Cardiology, a journal of the European Society of Cardiology (ESC). “Age is one of the …

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Uncategorized Strategies for slowing, stopping, or reversing Parkinson’s disease

Strategies for slowing, stopping, or reversing Parkinson’s disease

PD is a slowly progressive disorder that affects movement, muscle control, and balance. “Our understanding of PD pathophysiology has vastly improved compared to what we knew 20 years ago,” explained authors Tom Foltynie, MBBS, PhD, Department of Clinical and Movement Neurosciences, UCL Institute of Neurology & The National Hospital for Neurology and Neurosurgery, London, UK, …

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Uncategorized Vicious cycles and age-related diseases

Vicious cycles and age-related diseases

Statistical data indicate that the mortality rates due to all major age-related diseases increase exponentially with age. The MIPT researcher hypothesized that the reason behind this self-aggravating disease progression is the indefinite repetition of reaction cycles, which increases the harm from the initially noncritical changes in the body manyfold. It is these cycles that prospective …

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Uncategorized Exercise may protect against Alzheimer’s

Exercise may protect against Alzheimer’s

thletes know a vigorous workout can release a flood of endorphins: “feel-good” hormones that boost mood. Now there’s evidence that exercise produces another hormone that may improve memory and protect against Alzheimer’s disease, according to a study co-led by Ottavio Arancio, MD, PhD, a researcher at Columbia University’s Vagelos College of Physicians and Surgeons and …

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Uncategorized Conference looks to biological ‘pillars of aging’

Conference looks to biological ‘pillars of aging’

Rather than beginning with the discrete health conditions and concerns common among older adults, conference organizers took the unique approach of focusing on aging itself as a primary factor impacting multiple chronic diseases and the declining ability to rebound from health challenges (also known as “resilience”). In doing so, GEMSSTAR scholars advanced our understanding of …

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Uncategorized Relationships, stress, and sleep

Relationships, stress, and sleep

A new Personal Relationships study documents how the quality of a person’s romantic relationship and the life stress he or she experiences at two key points in early adulthood (at age 23 and 32) are related to sleep quality and quantity in middle adulthood (at age 37). Investigators found that people who have positive relationship …

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Uncategorized At the intersection of technology and aging 

At the intersection of technology and aging 

The latest issue of the journal The Gerontologist from The Gerontological Society of America contains 21 articles highlighting the state-of-the-art research regarding aging and technology, and offering guidance for the future. Among the findings are that older adults in certain demographic groups are less likely to use technology for health-related purposes; using the Internet to …

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Uncategorized How Nazis manufactured the idea of race

How Nazis manufactured the idea of race

“Race had to be manufactured in Germans’ minds and everyday lives, and one of the ways they manufactured race was by celebrating this unique mix of movements that made them different from other people, and the actual movement of Germans themselves became a mechanism to get people to think in racial terms,” Denning said. Take …

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