Researchers at Boston University School of Medicine (BUSM) have discovered that blocking a specific protein, may be a promising strategy to prevent the spread of castration-resistant prostate cancer (CRPC). Under the direction of BUSM’s Gerald V. Denis PhD, researchers have long studied a family of three closely related proteins, called BET bromodomain proteins, composed of …
Exposure to environmental pollutants can cause alterations in brain development that affect sexual development and fertility for several generations, according to findings to be presented in Lyon, at the European Society of Endocrinology annual meeting, ECE 2019. The offspring of pregnant rats exposed to a mixture of common endocrine-disrupting chemicals (EDCs), at doses equivalent to …
When making a complex decision, we often break the problem down into a series of smaller decisions. For example, when deciding how to treat a patient, a doctor may go through a hierarchy of steps — choosing a diagnostic test, interpreting the results, and then prescribing a medication. Making hierarchical decisions is straightforward when the …
Chronic insomnia disorder, which affects approximately 10 percent of adults, has a direct negative impact on cognitive function of people aged 45 and over, independent of the effect of other health issues. This is the primary finding from an analysis of sleep data from the pan-Canadian cohort of the Canadian Longitudinal Study on Aging. The …
Regular use of glucosamine supplements may be related to a lower risk of cardiovascular disease (CVD) events, suggests an analysis of data from the UK Biobank study, published in The BMJ today. The findings suggest that glucosamine may have benefits in preventing CVD events, such as coronary heart disease and stroke, and further clinical trials …
In a records review of 290 people at risk for Alzheimer’s disease, scientists at Johns Hopkins say they have identified an average level of biological and anatomical brain changes linked to Alzheimer’s disease that occur three to 10 years — some even more than 30 years — before the disease’s first recognizable symptoms appear. “Our …
A team of psychologists has found strong associations between working memory — a fundamental building block of a functioning mind — and three health-related factors: sleep, age, and depressed mood. The team also reports that each of these factors is associated with different aspects of working memory. Working memory is the part of short-term memory …
To deliver optimal treatment by 2040, a significant expansion of the chemotherapy workforce is needed. Between 2018 and 2040, the number of patients requiring first-line chemotherapy treatment each year is predicted to rise from 9.8 million to 15 million (53%) globally, if there were full application of evidence-based guidelines. This is according to a modelling …
Long-term stress has been linked with cardiovascular disease, but for people with depression, researchers say small, everyday stressors may be enough to diminish blood vessel function in otherwise healthy adults. A team of researchers led by Penn State found that among adults with depression, those who had experienced stress in the previous 24 hours had …
Researchers have discovered that instances in which outcomes are better than expected — finding an unexpectedly good parking spot, for example, or spotting a $20 bill on the sidewalk — improves memories of specific events. This is in addition to the long-established role that unexpectedly good outcomes have in influencing what are called integrated memories. …